ABSTRACT
摘要
Wereporta9-year-oldJapanesegirlwhopresentedwithmuscleweaknessandelevatedserumlevelsofmuscle-derivedenzymesfollowingmycoplasmainfection.Rhabdomyolysisormyositiswassuggestedbymagneticresonanceimagingandrepeatedfourtimeswithin4years.Eachepisodedevelopedfollowingrespiratoryinfectionandspontaneouslyrecovered.ThediagnosisofSj?gren’ssyndromewasmadebydecreasedsalivarysecretion,MRsialography,lipbiopsy,andpositiveanti-SSA/Roantibody.Giventherarityofrhabdomyolysis/myositis,recurrentepisodecouldbeinducedbyinfectiousdiseaseonthebasisofunderlyingSj?gren’ssyndrome.Conclusion:Sj?gren’ssyndromeshouldbeconsideredasanunderlyingdiseaseofrecurrentinfection-inducedrhabdomyolysis/myositis.
本文所述为一例9岁日籍女孩支原体感染后出现肌无力和血清肌源性酶水平升高。4年内行4次磁共振成像（MRI），提示横纹肌溶解症和肌炎。每次呼吸道感染后均出现症状，之后自发缓解。根据唾液分泌减少、MR涎腺造影、唇腺活检及抗SSA/Ro抗体阳性等指标诊断为干燥综合征。考虑到横纹肌溶解症/肌炎较为罕见，症状复发可能是由于以潜在的干燥综合征为基础的感染性疾病。结论：干燥综合征应视为复发性感染诱发的横纹肌溶解症/肌炎的潜在疾病。
Keywords:Childhood;Infection;Myositis;MycoplasmaPneumoniae;Sj?gren’sSyndrome
关键词：儿童；感染；肌炎；肺炎支原体；干燥综合征
INTRODUCTION
引言
Thediagnosisofrabdomyolysisormyositisisoftenchallenginginpediatricclinicalsettingbecauseofvariouspathogenesissuchasdrugs,infections,autoimmunity,andmetabolicdiseases.Sj?gren’ssyndrome(SS),anautoimmunedisorderprimarilyaffectingexocrinegland,isoften皮肤白癜风的治疗方法有哪些白癜风治疗需多少钱